USP19 deubiquitinates HDAC1/2 to regulate DNA damage repair and control chromosomal stability

Excessive accumulation of DNA damage will generate chromosome stress, leading to various chromosome abnormalities such as chromatin bridge and result in genomic instability. Orchestra procession and regulation of DNA damage repair are vital for keeping genome stability. Despite of the key role of HD...

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Detalles Bibliográficos
Autores principales: Wu, Min, Tu, Hai-qing, Chang, Yan, Tan, Bo, Wang, Guang, Zhou, Jie, Wang, Li, Mu, Rui, Zhang, Wei-na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356792/
https://www.ncbi.nlm.nih.gov/pubmed/27517492
http://dx.doi.org/10.18632/oncotarget.11116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356792/
https://www.ncbi.nlm.nih.gov/pubmed/27517492
http://dx.doi.org/10.18632/oncotarget.11116

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