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USP19 deubiquitinates HDAC1/2 to regulate DNA damage repair and control chromosomal stability
Excessive accumulation of DNA damage will generate chromosome stress, leading to various chromosome abnormalities such as chromatin bridge and result in genomic instability. Orchestra procession and regulation of DNA damage repair are vital for keeping genome stability. Despite of the key role of HD...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356792/ https://www.ncbi.nlm.nih.gov/pubmed/27517492 http://dx.doi.org/10.18632/oncotarget.11116 |