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The tissue inhibitor of metalloproteinases-1 (TIMP-1) promotes survival and migration of acute myeloid leukemia cells through CD63/PI3K/Akt/p21 signaling

We and others have shown that the Tissue Inhibitor of Metalloproteinases-1 (TIMP-1), a member of the inflammatory network exerting pleiotropic effects in the bone marrow (BM) microenvironment, regulates the survival and proliferation of different cell types, including normal hematopoietic progenitor...

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Detalles Bibliográficos
Autores principales: Forte, Dorian, Salvestrini, Valentina, Corradi, Giulia, Rossi, Lara, Catani, Lucia, Lemoli, Roberto M., Cavo, Michele, Curti, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356797/
https://www.ncbi.nlm.nih.gov/pubmed/27903985
http://dx.doi.org/10.18632/oncotarget.13664