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KRAS exon 2 codon 13 mutation is associated with a better prognosis than codon 12 mutation following lung metastasectomy in colorectal cancer

INTRODUCTION: The utilization of molecular markers as routinely used biomarkers is steadily increasing. We aimed to evaluate the potential different prognostic values of KRAS exon 2 codons 12 and 13 after lung metastasectomy in colorectal cancer (CRC). RESULTS: KRAS codon 12 mutations were observed...

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Detalles Bibliográficos
Autores principales: Renaud, Stéphane, Guerrera, Francesco, Seitlinger, Joseph, Costardi, Lorena, Schaeffer, Mickaël, Romain, Benoit, Mossetti, Claudio, Claire-Voegeli, Anne, Filosso, Pier Luigi, Legrain, Michèle, Ruffini, Enrico, Falcoz, Pierre-Emmanuel, Oliaro, Alberto, Massard, Gilbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356820/
https://www.ncbi.nlm.nih.gov/pubmed/27911859
http://dx.doi.org/10.18632/oncotarget.13697