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Icariside II activates EGFR-Akt-Nrf2 signaling and protects osteoblasts from dexamethasone

The potential effect of icariside II on dexamethasone-induced osteoblast cell damages was evaluated here. In MC3T3-E1 osteoblastic cells and the primary murine osteoblasts, co-treatment with icariside II dramatically attenuated dexamethasone- induced cell death and apoptosis. Icariside II activated...

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Detalles Bibliográficos
Autores principales: Liu, Weidong, Mao, Li, Ji, Feng, Chen, Fengli, Wang, Shouguo, Xie, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356826/
https://www.ncbi.nlm.nih.gov/pubmed/27911877
http://dx.doi.org/10.18632/oncotarget.13732