The antidepressant fluoxetine induces necrosis by energy depletion and mitochondrial calcium overload

Selective Serotonin Reuptake Inhibitor antidepressants, such as fluoxetine (Prozac), have been shown to induce cell death in cancer cells, paving the way for their potential use as cancer therapy. These compounds are able to increase cytosolic calcium concentration ([Ca(2+)](cyt)), but the involved...

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Detalles Bibliográficos
Autores principales: Charles, Emilie, Hammadi, Mehdi, Kischel, Philippe, Delcroix, Vanessa, Demaurex, Nicolas, Castelbou, Cyril, Vacher, Anne-Marie, Devin, Anne, Ducret, Thomas, Nunes, Paula, Vacher, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356874/
https://www.ncbi.nlm.nih.gov/pubmed/27911858
http://dx.doi.org/10.18632/oncotarget.13689

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356874/
https://www.ncbi.nlm.nih.gov/pubmed/27911858
http://dx.doi.org/10.18632/oncotarget.13689

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