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LEF1 reduces tumor progression and induces myodifferentiation in a subset of rhabdomyosarcoma

Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children and show characteristics of skeletal muscle differentiation. The two major RMS subtypes in children are alveolar (ARMS) and embryonal RMS (ERMS). We demonstrate that approximately 50% of ARMS and ERMS overexpress the LEF1/TCF...

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Detalles Bibliográficos
Autores principales:	Dräger, Julia, Simon-Keller, Katja, Pukrop, Tobias, Klemm, Florian, Wilting, Jörg, Sticht, Carsten, Dittmann, Kai, Schulz, Matthias, Leuschner, Ivo, Marx, Alexander, Hahn, Heidi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356880/ https://www.ncbi.nlm.nih.gov/pubmed/27965462 http://dx.doi.org/10.18632/oncotarget.13887

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