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Glucuronidation and UGT isozymes in bladder: new targets for the treatment of uroepithelial carcinomas?

Bladder cancer has been linked to numerous toxins which can be concentrated in the bladder after being absorbed into the blood and filtered by the kidneys. Excessive carcinogenic load to the bladder urothelium may result in the development of cancer. However, enzymes within the bladder can metaboliz...

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Detalles Bibliográficos
Autores principales: Sundararaghavan, Vikram L., Sindhwani, Puneet, Hinds, Terry D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356909/
https://www.ncbi.nlm.nih.gov/pubmed/27690298
http://dx.doi.org/10.18632/oncotarget.12277