A double blinded, placebo-controlled pilot study to examine reduction of CD34 (+)/CD117 (+)/CD133 (+) lymphoma progenitor cells and duration of remission induced by neoadjuvant valspodar in dogs with large B-cell lymphoma

We previously described a population of lymphoid progenitor cells (LPCs) in canine B-cell lymphoma defined by retention of the early progenitor markers CD34 and CD117 and “slow proliferation” molecular signatures that persist in the xenotransplantation setting. We examined whether valspodar, a selec...

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Detalles Bibliográficos
Autores principales: Ito, Daisuke, Childress, Michael, Mason, Nicola, Winter, Amber, O’Brien, Timothy, Henson, Michael, Borgatti, Antonella, Lewellen, Mitzi, Krick, Erika, Stewart, Jane, Lahrman, Sarah, Rajwa, Bartek, Scott, Milcah C, Seelig, Davis, Koopmeiners, Joseph, Ruetz, Stephan, Modiano, Jaime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357040/
https://www.ncbi.nlm.nih.gov/pubmed/28357033
http://dx.doi.org/10.12688/f1000research.6055.3

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