Target DNA bending by the Mu transpososome promotes careful transposition and prevents its reversal

The transposition of bacteriophage Mu serves as a model system for understanding DDE transposases and integrases. All available structures of these enzymes at the end of the transposition reaction, including Mu, exhibit significant bends in the transposition target site DNA. Here we use Mu to invest...

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Detalles Bibliográficos
Autores principales: Fuller, James R, Rice, Phoebe A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357137/
https://www.ncbi.nlm.nih.gov/pubmed/28177285
http://dx.doi.org/10.7554/eLife.21777

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357137/
https://www.ncbi.nlm.nih.gov/pubmed/28177285
http://dx.doi.org/10.7554/eLife.21777

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