Opposing effects on the cell cycle of T lymphocytes by Fbxo7 via Cdk6 and p27

G(1) phase cell cycle proteins, such as cyclin-dependent kinase 6 (Cdk6) and its activating partners, the D-type cyclins, are important regulators of T-cell development and function. An F-box protein, called F-box only protein 7 (Fbxo7), acts as a cell cycle regulator by enhancing cyclin D-Cdk6 comp...

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Detalles Bibliográficos
Autores principales: Patel, Shachi P., Randle, Suzanne J., Gibbs, Sarah, Cooke, Anne, Laman, Heike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357273/
https://www.ncbi.nlm.nih.gov/pubmed/27915416
http://dx.doi.org/10.1007/s00018-016-2427-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357273/
https://www.ncbi.nlm.nih.gov/pubmed/27915416
http://dx.doi.org/10.1007/s00018-016-2427-3

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