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Opposing effects on the cell cycle of T lymphocytes by Fbxo7 via Cdk6 and p27
G(1) phase cell cycle proteins, such as cyclin-dependent kinase 6 (Cdk6) and its activating partners, the D-type cyclins, are important regulators of T-cell development and function. An F-box protein, called F-box only protein 7 (Fbxo7), acts as a cell cycle regulator by enhancing cyclin D-Cdk6 comp...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357273/ https://www.ncbi.nlm.nih.gov/pubmed/27915416 http://dx.doi.org/10.1007/s00018-016-2427-3 |