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Sirtuins and Their Roles in Brain Aging and Neurodegenerative Disorders

Sirtuins (SIRT1–SIRT7) are unique histone deacetylases (HDACs) whose activity depends on NAD(+) levels and thus on the cellular metabolic status. SIRTs regulate energy metabolism and mitochondrial function. They orchestrate the stress response and damage repair. Through these functions sirtuins modu...

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Detalles Bibliográficos
Autores principales:	Jęśko, Henryk, Wencel, Przemysław, Strosznajder, Robert P., Strosznajder, Joanna B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2016
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357501/ https://www.ncbi.nlm.nih.gov/pubmed/27882448 http://dx.doi.org/10.1007/s11064-016-2110-y

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