Risk algorithms that include pathology adjustment for HER2 amplification need to make further downward adjustments in likelihood scores

To assess the need for adjustment in the likelihood of germline BRCA1/2 mutations in women with HER2+ breast cancers. We analysed primary mutation screens on women with breast cancer with unequivocal HER2 overexpression and assessed the likelihood of BRCA1/BRCA2 mutations by age, oestrogen receptor...

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Detalles Bibliográficos
Autores principales: Evans, D. G., Woodward, E. R., Howell, S. J., Verhoef, S., Howell, A., Lalloo, F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357509/
https://www.ncbi.nlm.nih.gov/pubmed/27796713
http://dx.doi.org/10.1007/s10689-016-9942-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357509/
https://www.ncbi.nlm.nih.gov/pubmed/27796713
http://dx.doi.org/10.1007/s10689-016-9942-0

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