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Risk algorithms that include pathology adjustment for HER2 amplification need to make further downward adjustments in likelihood scores
To assess the need for adjustment in the likelihood of germline BRCA1/2 mutations in women with HER2+ breast cancers. We analysed primary mutation screens on women with breast cancer with unequivocal HER2 overexpression and assessed the likelihood of BRCA1/BRCA2 mutations by age, oestrogen receptor...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Netherlands
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357509/ https://www.ncbi.nlm.nih.gov/pubmed/27796713 http://dx.doi.org/10.1007/s10689-016-9942-0 |