Data on chemical activation of Wnt/β-catenin during axolotl limb regeneration

Limb amputation in axolotls was performed to obtain data demonstrating that a chemical agonist of Wnt (int-related protein)/β-catenin signalling can have a role in axolotl limb regeneration (Wischin et al., 2017) [1]. The data revealed that active β-catenin protein was present during limb regenerati...

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Detalles Bibliográficos
Autores principales: Wischin, Sabina, Castañeda-Patlán, Cristina, Robles-Flores, Martha, Chimal-Monroy, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Data Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357679/
https://www.ncbi.nlm.nih.gov/pubmed/28349103
http://dx.doi.org/10.1016/j.dib.2017.02.048
Descripción
Sumario:Limb amputation in axolotls was performed to obtain data demonstrating that a chemical agonist of Wnt (int-related protein)/β-catenin signalling can have a role in axolotl limb regeneration (Wischin et al., 2017) [1]. The data revealed that active β-catenin protein was present during limb regeneration in some Leydig cells in the epithelium; after the chemical treatment, it was observed in more Leydig cells. In addition, the chemical agonist of Wnt generated distinct limb malformation.

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