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Impact of Adverse Events Following Immunization in Viet Nam in 2013 on chronic hepatitis B infection()
Adverse Events Following Immunization in Viet Nam in 2013 led to substantial reductions in hepatitis B vaccination coverage (both the birth dose and the three-dose series). In order to estimate the impact of the reduction in vaccination coverage on hepatitis B transmission and future mortality, a wi...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357724/ https://www.ncbi.nlm.nih.gov/pubmed/26055296 http://dx.doi.org/10.1016/j.vaccine.2015.05.067 |
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author | Li, Xi Wiesen, Eric Diorditsa, Sergey Toda, Kohei Duong, Thi Hong Nguyen, Lien Huong Nguyen, Van Cuong Nguyen, Tran Hien |
author_facet | Li, Xi Wiesen, Eric Diorditsa, Sergey Toda, Kohei Duong, Thi Hong Nguyen, Lien Huong Nguyen, Van Cuong Nguyen, Tran Hien |
author_sort | Li, Xi |
collection | PubMed |
description | Adverse Events Following Immunization in Viet Nam in 2013 led to substantial reductions in hepatitis B vaccination coverage (both the birth dose and the three-dose series). In order to estimate the impact of the reduction in vaccination coverage on hepatitis B transmission and future mortality, a widely-used mathematical model was applied to the data from Viet Nam. Using the model, we estimated the number of chronic infections and deaths that are expected to occur in the birth cohort in 2013 and the number of excessive infections and deaths attributable to the drop in immunization coverage in 2013. An excess of 90,137 chronic infections and 17,456 future deaths were estimated to occur in the 2013 birth cohort due to the drop in vaccination coverage. This analysis highlights the importance of maintaining high vaccination coverage and swiftly responding to reported Adverse Events Following Immunization in order to regain consumer confidence in the hepatitis B vaccine. |
format | Online Article Text |
id | pubmed-5357724 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Elsevier Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-53577242017-03-28 Impact of Adverse Events Following Immunization in Viet Nam in 2013 on chronic hepatitis B infection() Li, Xi Wiesen, Eric Diorditsa, Sergey Toda, Kohei Duong, Thi Hong Nguyen, Lien Huong Nguyen, Van Cuong Nguyen, Tran Hien Vaccine Article Adverse Events Following Immunization in Viet Nam in 2013 led to substantial reductions in hepatitis B vaccination coverage (both the birth dose and the three-dose series). In order to estimate the impact of the reduction in vaccination coverage on hepatitis B transmission and future mortality, a widely-used mathematical model was applied to the data from Viet Nam. Using the model, we estimated the number of chronic infections and deaths that are expected to occur in the birth cohort in 2013 and the number of excessive infections and deaths attributable to the drop in immunization coverage in 2013. An excess of 90,137 chronic infections and 17,456 future deaths were estimated to occur in the 2013 birth cohort due to the drop in vaccination coverage. This analysis highlights the importance of maintaining high vaccination coverage and swiftly responding to reported Adverse Events Following Immunization in order to regain consumer confidence in the hepatitis B vaccine. Elsevier Science 2016-02-03 /pmc/articles/PMC5357724/ /pubmed/26055296 http://dx.doi.org/10.1016/j.vaccine.2015.05.067 Text en © 2015 World Health Organization; licensee Elsevier http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Article Li, Xi Wiesen, Eric Diorditsa, Sergey Toda, Kohei Duong, Thi Hong Nguyen, Lien Huong Nguyen, Van Cuong Nguyen, Tran Hien Impact of Adverse Events Following Immunization in Viet Nam in 2013 on chronic hepatitis B infection() |
title | Impact of Adverse Events Following Immunization in Viet Nam in 2013 on chronic hepatitis B infection() |
title_full | Impact of Adverse Events Following Immunization in Viet Nam in 2013 on chronic hepatitis B infection() |
title_fullStr | Impact of Adverse Events Following Immunization in Viet Nam in 2013 on chronic hepatitis B infection() |
title_full_unstemmed | Impact of Adverse Events Following Immunization in Viet Nam in 2013 on chronic hepatitis B infection() |
title_short | Impact of Adverse Events Following Immunization in Viet Nam in 2013 on chronic hepatitis B infection() |
title_sort | impact of adverse events following immunization in viet nam in 2013 on chronic hepatitis b infection() |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357724/ https://www.ncbi.nlm.nih.gov/pubmed/26055296 http://dx.doi.org/10.1016/j.vaccine.2015.05.067 |
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