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Negative Regulators of an RNAi-Heterochromatin Positive Feedback Loop Safeguard Somatic Genome Integrity in Tetrahymena

RNAi-mediated positive feedback loops are pivotal for the maintenance of heterochromatin, but how they are downregulated at heterochromatin-euchromatin borders is not well understood. In the ciliated protozoan Tetrahymena, heterochromatin is formed exclusively on the sequences that are removed from...

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Detalles Bibliográficos
Autores principales:	Suhren, Jan H., Noto, Tomoko, Kataoka, Kensuke, Gao, Shan, Liu, Yifan, Mochizuki, Kazufumi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357732/ https://www.ncbi.nlm.nih.gov/pubmed/28273462 http://dx.doi.org/10.1016/j.celrep.2017.02.024

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