Lamotrigine-related pseudolymphoma presenting as cervical lymphadenopathy

Immune-mediated drug reactions are a potentially life-threatening complication of antiseizure medications. Drug hypersensitivity syndrome (DHS) is the best recognised of these, presenting with fever, eosinophilia, rash and internal organ involvement. Isolated lymphadenopathy is a less recognized imm...

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Detalles Bibliográficos
Autores principales: Mulroy, Eoin, Walker, Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357739/
https://www.ncbi.nlm.nih.gov/pubmed/28348962
http://dx.doi.org/10.1016/j.ebcr.2016.12.004
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author Mulroy, Eoin
Walker, Elizabeth
author_facet Mulroy, Eoin
Walker, Elizabeth
author_sort Mulroy, Eoin
collection PubMed
description Immune-mediated drug reactions are a potentially life-threatening complication of antiseizure medications. Drug hypersensitivity syndrome (DHS) is the best recognised of these, presenting with fever, eosinophilia, rash and internal organ involvement. Isolated lymphadenopathy is a less recognized immune-mediated reaction to antiseizure drugs such as lamotrigine. We describe the case of a 24-year-old woman who developed lamotrigine-related bilateral cervical lymphadenopathy (pseudolymphoma) fifteen months following therapy initiation. This is the second such case reported in the medical literature.
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spelling pubmed-53577392017-03-27 Lamotrigine-related pseudolymphoma presenting as cervical lymphadenopathy Mulroy, Eoin Walker, Elizabeth Epilepsy Behav Case Rep Case Report Immune-mediated drug reactions are a potentially life-threatening complication of antiseizure medications. Drug hypersensitivity syndrome (DHS) is the best recognised of these, presenting with fever, eosinophilia, rash and internal organ involvement. Isolated lymphadenopathy is a less recognized immune-mediated reaction to antiseizure drugs such as lamotrigine. We describe the case of a 24-year-old woman who developed lamotrigine-related bilateral cervical lymphadenopathy (pseudolymphoma) fifteen months following therapy initiation. This is the second such case reported in the medical literature. Elsevier 2017-01-18 /pmc/articles/PMC5357739/ /pubmed/28348962 http://dx.doi.org/10.1016/j.ebcr.2016.12.004 Text en © 2017 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Mulroy, Eoin
Walker, Elizabeth
Lamotrigine-related pseudolymphoma presenting as cervical lymphadenopathy
title Lamotrigine-related pseudolymphoma presenting as cervical lymphadenopathy
title_full Lamotrigine-related pseudolymphoma presenting as cervical lymphadenopathy
title_fullStr Lamotrigine-related pseudolymphoma presenting as cervical lymphadenopathy
title_full_unstemmed Lamotrigine-related pseudolymphoma presenting as cervical lymphadenopathy
title_short Lamotrigine-related pseudolymphoma presenting as cervical lymphadenopathy
title_sort lamotrigine-related pseudolymphoma presenting as cervical lymphadenopathy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357739/
https://www.ncbi.nlm.nih.gov/pubmed/28348962
http://dx.doi.org/10.1016/j.ebcr.2016.12.004
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AT walkerelizabeth lamotriginerelatedpseudolymphomapresentingascervicallymphadenopathy

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