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HSP70-1 is required for interleukin-5-induced angiogenic responses through eNOS pathway

We report a pivotal role for IL-5 as an angiogenic activator. IL-5 increased proliferation, migration and colony tube formation in HUVECs associated with the phosphorylation of ERK and AKT/eNOS, and promoted microvessel sprouting from an angiogenesis animal model. The angiogenic effects were confirm...

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Detalles Bibliográficos
Autores principales:	Park, Sung Lyea, Chung, Tae-Wook, Kim, Sangtae, Hwang, Byungdoo, Kim, Jung Min, Lee, Hwan Myung, Cha, Hee-Jae, Seo, Yoonhee, Choe, Soo Young, Ha, Ki-Tae, Kim, Gonhyung, Yun, Seok-Joong, Park, Sung-Soo, Choi, Yung Hyun, Kim, Bo Kyung, Kim, Won-Tae, Cha, Eun-Jong, Patterson, Cam, Kim, Wun-Jae, Moon, Sung-Kwon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357797/ https://www.ncbi.nlm.nih.gov/pubmed/28317868 http://dx.doi.org/10.1038/srep44687

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