Mutual reinforcement between telomere capping and canonical Wnt signalling in the intestinal stem cell niche

Critical telomere shortening (for example, secondary to partial telomerase deficiency in the rare disease dyskeratosis congenita) causes tissue pathology, but underlying mechanisms are not fully understood. Mice lacking telomerase (for example, mTR(−/−) telomerase RNA template mutants) provide a mod...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Ting-Lin B., Chen, Qijun, Deng, Jennifer T., Jagannathan, Geetha, Tobias, John W., Schultz, David C., Wang, Shan, Lengner, Christopher J., Rustgi, Anil K., Lynch, John P., Johnson, F. Brad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357864/
https://www.ncbi.nlm.nih.gov/pubmed/28303901
http://dx.doi.org/10.1038/ncomms14766

Ejemplares similares

Ejemplares similares