BDE-99 impairs differentiation of human and mouse NPCs into the oligodendroglial lineage by species-specific modes of action

Polybrominated diphenyl ethers (PBDEs) are bioaccumulating flame retardants causing developmental neurotoxicity (DNT) in humans and rodents. Their DNT effects are suspected to involve thyroid hormone (TH) signaling disruption. Here, we tested the hypothesis whether disturbance of neural progenitor c...

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Detalles Bibliográficos
Autores principales: Dach, Katharina, Bendt, Farina, Huebenthal, Ulrike, Giersiefer, Susanne, Lein, Pamela J., Heuer, Heike, Fritsche, Ellen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357893/
https://www.ncbi.nlm.nih.gov/pubmed/28317842
http://dx.doi.org/10.1038/srep44861

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