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Priming of transcriptional memory responses via the chromatin accessibility landscape in T cells
Memory T cells exhibit transcriptional memory and “remember” their previous pathogenic encounter to increase transcription on re-infection. However, how this transcriptional priming response is regulated is unknown. Here we performed global FAIRE-seq profiling of chromatin accessibility in a human T...
Autores principales: | Tu, Wen Juan, Hardy, Kristine, Sutton, Christopher R., McCuaig, Robert, Li, Jasmine, Dunn, Jenny, Tan, Abel, Brezar, Vedran, Morris, Melanie, Denyer, Gareth, Lee, Sau Kuen, Turner, Stephen J., Seddiki, Nabila, Smith, Corey, Khanna, Rajiv, Rao, Sudha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357947/ https://www.ncbi.nlm.nih.gov/pubmed/28317936 http://dx.doi.org/10.1038/srep44825 |
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