Cargando…

Priming of transcriptional memory responses via the chromatin accessibility landscape in T cells

Memory T cells exhibit transcriptional memory and “remember” their previous pathogenic encounter to increase transcription on re-infection. However, how this transcriptional priming response is regulated is unknown. Here we performed global FAIRE-seq profiling of chromatin accessibility in a human T...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tu, Wen Juan, Hardy, Kristine, Sutton, Christopher R., McCuaig, Robert, Li, Jasmine, Dunn, Jenny, Tan, Abel, Brezar, Vedran, Morris, Melanie, Denyer, Gareth, Lee, Sau Kuen, Turner, Stephen J., Seddiki, Nabila, Smith, Corey, Khanna, Rajiv, Rao, Sudha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357947/ https://www.ncbi.nlm.nih.gov/pubmed/28317936 http://dx.doi.org/10.1038/srep44825

Ejemplares similares

Chromatinized Protein Kinase C-θ: Can It Escape the Clutches of NF-κB?
por: Sutcliffe, Elissa L., et al.
Publicado: (2012)

PKC-Theta in Regulatory and Effector T-cell Functions
por: Brezar, Vedran, et al.
Publicado: (2015)

Nuclear PKC-θ facilitates rapid transcriptional responses in human memory CD4(+) T cells through p65 and H2B phosphorylation
por: Li, Jasmine, et al.
Publicado: (2016)

Multi-layered epigenetic mechanisms contribute to transcriptional memory in T lymphocytes
por: Dunn, Jennifer, et al.
Publicado: (2015)

T-Regulatory Cells and Vaccination “Pay Attention and Do Not Neglect Them”: Lessons from HIV and Cancer Vaccine Trials
por: Brezar, Vedran, et al.
Publicado: (2016)

Identification of chromatin accessibility domains in human breast cancer stem cells
por: Hardy, K., et al.
Publicado: (2016)

Targeting Nuclear LSD1 to Reprogram Cancer Cells and Reinvigorate Exhausted T Cells via a Novel LSD1-EOMES Switch
por: Tu, Wen Juan, et al.
Publicado: (2020)

Differential Roles for DUSP Family Members in Epithelial-to-Mesenchymal Transition and Cancer Stem Cell Regulation in Breast Cancer
por: Boulding, Tara, et al.
Publicado: (2016)

Negative modulation of suppressive HIV-specific regulatory T cells by IL-2 adjuvanted therapeutic vaccine
por: Brezar, Vedran, et al.
Publicado: (2017)

Lysine-Specific Histone Demethylase 1A Regulates Macrophage Polarization and Checkpoint Molecules in the Tumor Microenvironment of Triple-Negative Breast Cancer
por: Tan, Abel H. Y., et al.
Publicado: (2019)

PKC-Theta is a Novel SC35 Splicing Factor Regulator in Response to T Cell Activation
por: McCuaig, Robert Duncan, et al.
Publicado: (2015)

Decreased HIV-Specific T-Regulatory Responses Are Associated with Effective DC-Vaccine Induced Immunity
por: Brezar, Vedran, et al.
Publicado: (2015)

Pelvic congestion syndrome
por: Robertson, Meiri, et al.
Publicado: (2015)

Immunostimulating Commensal Bacteria and Their Potential Use as Therapeutics
por: McCuaig, Bonita, et al.
Publicado: (2023)

A Phase 1 Proof of Concept Study Evaluating the Addition of an LSD1 Inhibitor to Nab-Paclitaxel in Advanced or Metastatic Breast Cancer (EPI-PRIMED)
por: Prasanna, Thiru, et al.
Publicado: (2022)

To B or Not to B: (Anti)bodies of Evidence on the Crime Scene of Type 1 Diabetes?
por: Mallone, Roberto, et al.
Publicado: (2011)

Low SAMHD1 expression following T-cell activation and proliferation renders CD4(+) T cells susceptible to HIV-1
por: Ruffin, Nicolas, et al.
Publicado: (2015)

Nurse Practitioners in Orthopaedic Surgical Settings: A Review of the Literature
por: Spence, Brittany G., et al.
Publicado: (2019)

The bivalve Thyasira cf. gouldi hosts chemoautotrophic symbiont populations with strain level diversity
por: McCuaig, Bonita, et al.
Publicado: (2017)

Methodological challenges in the comparison of infant fMRI across age groups
por: Cusack, Rhodri, et al.
Publicado: (2017)

Vulvar involvement in epidermolysis bullosa: Case series
por: Dang, Julie, et al.
Publicado: (2021)

Exploring a Complementary Stress Management and Wellbeing Intervention Model for Teachers: Participant Experience
por: Hepburn, Stevie-Jae, et al.
Publicado: (2021)

The Relationship between Mindful Attention Awareness, Perceived Stress and Subjective Wellbeing
por: Hepburn, Stevie-Jae, et al.
Publicado: (2021)

T Cell Recognition of Autoantigens in Human Type 1 Diabetes: Clinical Perspectives
por: Mallone, Roberto, et al.
Publicado: (2011)

Targeting novel LSD1-dependent ACE2 demethylation domains inhibits SARS-CoV-2 replication
por: Tu, Wen Juan, et al.
Publicado: (2021)

Author Correction: Targeting novel LSD1-dependent ACE2 demethylation domains inhibits SARS-CoV-2 replication
por: Tu, Wen Juan, et al.
Publicado: (2021)

Fathers’ Experiences and Perspectives of Breastfeeding: A Scoping Review
por: Sihota, Harvinder, et al.
Publicado: (2019)

Metagenomic analysis suggests broad metabolic potential in extracellular symbionts of the bivalve Thyasira cf. gouldi
por: McCuaig, Bonita, et al.
Publicado: (2020)

A Complementary Intervention to Promote Wellbeing and Stress Management for Early Career Teachers
por: Hepburn, Stevie-Jae, et al.
Publicado: (2021)

Extramedullary hematopoiesis secondary to COVID-19: A first case report in a newborn
por: Caudrelier, Nicolas, et al.
Publicado: (2022)

LSD1 activation promotes inducible EMT programs and modulates the tumour microenvironment in breast cancer
por: Boulding, T., et al.
Publicado: (2018)

Author Correction: LSD1 activation promotes inducible EMT programs and modulates the tumour microenvironment in breast cancer
por: Boulding, T., et al.
Publicado: (2019)

Nuclear-Biased DUSP6 Expression is Associated with Cancer Spreading Including Brain Metastasis in Triple-Negative Breast Cancer
por: Wu, Fan, et al.
Publicado: (2019)

Sexual Health in Men With Traumatic Spinal Cord Injuries: A Review and Recommendations for Primary Health-Care Providers
por: Aikman, Kirsten, et al.
Publicado: (2018)

Eating Disorders in Males: How Primary Care Providers Can Improve Recognition, Diagnosis, and Treatment
por: Sangha, Simrin, et al.
Publicado: (2019)

In vivo inhibition of nuclear ACE2 translocation protects against SARS-CoV-2 replication and lung damage through epigenetic imprinting
por: Tu, Wen Juan, et al.
Publicado: (2023)

Expression of the Bgp gene and characterization of mouse colon biliary glycoprotein isoforms
por: McCuaig, Kimberly, et al.
Publicado: (1993)

Psychosocial Interventions for Women with a BRCA1 or BRCA2 Mutation: A Scoping Review
por: Boghosian, Talin, et al.
Publicado: (2021)

COVID-19 and HIV-Associated Immune Reconstitution Inflammatory Syndrome: Emergence of Pathogen-Specific Immune Responses Adding Fuel to the Fire
por: Seddiki, Nabila, et al.
Publicado: (2021)

A National Needs Assessment of Canadian Nurse Practitioners Regarding Cannabis for Therapeutic Purposes
por: Balneaves, Lynda G., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_b1kg4cev4t6qlsuumr5ofs3u01