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Adoptive immunotherapy of cancer with polyclonal, 10(8)-fold hyperexpanded, CD4(+ )and CD8(+ )T cells
T cell-mediated cancer immunotherapy is dose dependent and optimally requires participation of antigen-specific CD4(+ )and CD8(+ )T cells. Here, we isolated tumor-sensitized T cells and activated them in vitro using conditions that led to greater than 10(8)-fold numerical hyperexpansion of either th...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2004
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC535812/ https://www.ncbi.nlm.nih.gov/pubmed/15566571 http://dx.doi.org/10.1186/1479-5876-2-41 |