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C3 glomerulopathy associated to multiple myeloma successfully treated by autologous stem cell transplant

A 32-year-old male presented with advanced renal failure and nephrotic proteinuria due to lambda light chain multiple myeloma. Renal biopsy showed a proliferative glomerulonephritis with isolated C3 deposits. Renal recovery was obtained after chemotherapy and autologous stem cell transplant. We revi...

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Detalles Bibliográficos
Autores principales: Hamzi, M. A., Zniber, A., Badaoui, G. E., Mahtat, E., Alhamany, Z., Bayahia, R., Ouzeddoun, N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358157/
https://www.ncbi.nlm.nih.gov/pubmed/28356669
http://dx.doi.org/10.4103/0971-4065.181884
Descripción
Sumario:A 32-year-old male presented with advanced renal failure and nephrotic proteinuria due to lambda light chain multiple myeloma. Renal biopsy showed a proliferative glomerulonephritis with isolated C3 deposits. Renal recovery was obtained after chemotherapy and autologous stem cell transplant. We review previously described cases of C3 glomerulopathy associated with monoclonal gammopathy.