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Impact of Grapefruit Juice on the Antiplatelet Activity of Loading and Maintenance Doses of Clopidogrel in Healthy Volunteers

BACKGROUND: Grapefruit juice impacts the metabolism of a number of drugs via inhibition of a variety of metabolic enzymes. This study evaluated the impact of grapefruit juice on the antiplatelet activity of a loading dose and 7 days of maintenance therapy with clopidogrel. METHODS: Healthy volunteer...

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Detalles Bibliográficos
Autores principales:	Campbell, Jennifer A., Teply, Robyn, Mooss, Aryan N., Hilleman, Daniel E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elmer Press 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358272/ https://www.ncbi.nlm.nih.gov/pubmed/28392868 http://dx.doi.org/10.14740/cr307w

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