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Incidence of Gastrointestinal Bleeding After Percutaneous Coronary Intervention: A Single Center Experience

BACKGROUND: Gastrointestinal (GI) bleeding is a hemorrhagic complication after percutaneous coronary intervention in patients with acute myocardial infarction. The purpose of the study is to determine predictors of GI bleeding and impact of GI bleeding on the patients undergoing percutaneous coronar...

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Detalles Bibliográficos
Autor principal: Aziz, Fahad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elmer Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358273/
https://www.ncbi.nlm.nih.gov/pubmed/28392869
http://dx.doi.org/10.14740/cr322w
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author Aziz, Fahad
author_facet Aziz, Fahad
author_sort Aziz, Fahad
collection PubMed
description BACKGROUND: Gastrointestinal (GI) bleeding is a hemorrhagic complication after percutaneous coronary intervention in patients with acute myocardial infarction. The purpose of the study is to determine predictors of GI bleeding and impact of GI bleeding on the patients undergoing percutaneous coronary intervention. METHODS: GI bleeding occurred in 6 (7.1%) of 84 patients with STEMI/NSETMI (ST-segment elevated myocardial infarction/Non ST-segment elevated myocardial infarction) undergoing primary percutaneous coronary intervention. RESULTS: Univariate analysis demonstrates that patients with GI bleeding had a significantly higher previous GI bleeding (16.66% vs. 8.6%, P < 0.001). Higher Killip classification at presentation was associated with higher incidence of GI bleeding (61% vs. 18%, P < 0.01). The use of proton pump inhibitors did not reduce the risk of GI bleeding. The GI bleeding in these patients was associated with higher mortality and morbidity in the post percutaneous coronary intervention period. CONCLUSION: Although, GI bleeding in patients with MI significantly increases mortality and morbidity, previous GI bleeding and higher Killip class are associated with higher incidence of GI bleeding. High-risk patients for GI bleeding can be identified at presentation.
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spelling pubmed-53582732017-04-07 Incidence of Gastrointestinal Bleeding After Percutaneous Coronary Intervention: A Single Center Experience Aziz, Fahad Cardiol Res Original Article BACKGROUND: Gastrointestinal (GI) bleeding is a hemorrhagic complication after percutaneous coronary intervention in patients with acute myocardial infarction. The purpose of the study is to determine predictors of GI bleeding and impact of GI bleeding on the patients undergoing percutaneous coronary intervention. METHODS: GI bleeding occurred in 6 (7.1%) of 84 patients with STEMI/NSETMI (ST-segment elevated myocardial infarction/Non ST-segment elevated myocardial infarction) undergoing primary percutaneous coronary intervention. RESULTS: Univariate analysis demonstrates that patients with GI bleeding had a significantly higher previous GI bleeding (16.66% vs. 8.6%, P < 0.001). Higher Killip classification at presentation was associated with higher incidence of GI bleeding (61% vs. 18%, P < 0.01). The use of proton pump inhibitors did not reduce the risk of GI bleeding. The GI bleeding in these patients was associated with higher mortality and morbidity in the post percutaneous coronary intervention period. CONCLUSION: Although, GI bleeding in patients with MI significantly increases mortality and morbidity, previous GI bleeding and higher Killip class are associated with higher incidence of GI bleeding. High-risk patients for GI bleeding can be identified at presentation. Elmer Press 2014-02 2014-02-27 /pmc/articles/PMC5358273/ /pubmed/28392869 http://dx.doi.org/10.14740/cr322w Text en Copyright 2014, Aziz http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Aziz, Fahad
Incidence of Gastrointestinal Bleeding After Percutaneous Coronary Intervention: A Single Center Experience
title Incidence of Gastrointestinal Bleeding After Percutaneous Coronary Intervention: A Single Center Experience
title_full Incidence of Gastrointestinal Bleeding After Percutaneous Coronary Intervention: A Single Center Experience
title_fullStr Incidence of Gastrointestinal Bleeding After Percutaneous Coronary Intervention: A Single Center Experience
title_full_unstemmed Incidence of Gastrointestinal Bleeding After Percutaneous Coronary Intervention: A Single Center Experience
title_short Incidence of Gastrointestinal Bleeding After Percutaneous Coronary Intervention: A Single Center Experience
title_sort incidence of gastrointestinal bleeding after percutaneous coronary intervention: a single center experience
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358273/
https://www.ncbi.nlm.nih.gov/pubmed/28392869
http://dx.doi.org/10.14740/cr322w
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