Cargando…
Synergy of cAMP and calcium signaling pathways in CFTR regulation
Cystic fibrosis results from mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel, leading to defective apical chloride transport. Patients also experience overactivation of inflammatory processes, including increased calcium signaling. Many investigations hav...
Autores principales: | Bozoky, Zoltan, Ahmadi, Saumel, Milman, Tal, Kim, Tae Hun, Du, Kai, Di Paola, Michelle, Pasyk, Stan, Pekhletski, Roman, Keller, Jacob P., Bear, Christine E., Forman-Kay, Julie D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358358/ https://www.ncbi.nlm.nih.gov/pubmed/28242698 http://dx.doi.org/10.1073/pnas.1613546114 |
Ejemplares similares
-
Functional Rescue of F508del-CFTR Using Small Molecule Correctors
por: Molinski, Steven, et al.
Publicado: (2012) -
Direct activation of a phospholipase by cyclic GMP-AMP in El Tor Vibrio cholerae
por: Severin, Geoffrey B., et al.
Publicado: (2018) -
Small-molecule allosteric activators of PDE4 long form cyclic AMP phosphodiesterases
por: Omar, Faisa, et al.
Publicado: (2019) -
AMP-activated protein kinase activation and NADPH oxidase inhibition by inorganic nitrate and nitrite prevent liver steatosis
por: Cordero-Herrera, Isabel, et al.
Publicado: (2019) -
An endogenous dAMP ligand in Bacillus subtilis class Ib RNR promotes assembly of a noncanonical dimer for regulation by dATP
por: Parker, Mackenzie J., et al.
Publicado: (2018)