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Differential S1P Receptor Profiles on M1- and M2-Polarized Macrophages Affect Macrophage Cytokine Production and Migration

Introduction. Macrophages are key players in complex biological processes. In response to environmental signals, macrophages undergo polarization towards a proinflammatory (M1) or anti-inflammatory (M2) phenotype. Sphingosine 1-phosphate (S1P) is a bioactive lysophospholipid that acts via 5 G-protei...

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Detalles Bibliográficos
Autores principales:	Müller, Jan, von Bernstorff, Wolfram, Heidecke, Claus-Dieter, Schulze, Tobias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358463/ https://www.ncbi.nlm.nih.gov/pubmed/28367448 http://dx.doi.org/10.1155/2017/7584621

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