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Rutin Protects against Pirarubicin-Induced Cardiotoxicity through TGF-β1-p38 MAPK Signaling Pathway

We investigated the potential protective effect of rutinum (RUT) against pirarubicin- (THP-) induced cardiotoxicity. THP was used to induce toxicity in rat H9c2 cardiomyoblasts. Positive control cells were pretreated with a cardioprotective agent dexrazoxane (DZR) prior to treatment with THP. Some o...

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Detalles Bibliográficos
Autores principales:	Wang, Yadi, Zhang, Yang, Sun, Bo, Tong, Qing, Ren, Liqun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358477/ https://www.ncbi.nlm.nih.gov/pubmed/28367221 http://dx.doi.org/10.1155/2017/1759385

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