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Conducting the finale of DNA replication
Anomalies in dismantling the machinery of DNA replication can compromise genome integrity and contribute to tumorigenesis and aging. In this issue of Genes & Development, Dewar and colleagues (pp. 275–290) identified an E3 ubiquitin ligase, CUL2(LRR2), that modifies a subunit of the replicative...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory Press
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358719/ https://www.ncbi.nlm.nih.gov/pubmed/28270514 http://dx.doi.org/10.1101/gad.297184.117 |