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ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair
Chromatin connects DNA damage response factors to sites of damaged DNA to promote the signaling and repair of DNA lesions. The histone H2A variants H2AX, H2AZ, and macroH2A represent key chromatin constituents that facilitate DNA repair. Through proteomic screening of these variants, we identified Z...
Autores principales: | Leung, Justin W.C., Makharashvili, Nodar, Agarwal, Poonam, Chiu, Li-Ya, Pourpre, Renaud, Cammarata, Michael B., Cannon, Joe R., Sherker, Alana, Durocher, Daniel, Brodbelt, Jennifer S., Paull, Tanya T., Miller, Kyle M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358723/ https://www.ncbi.nlm.nih.gov/pubmed/28242625 http://dx.doi.org/10.1101/gad.292516.116 |
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