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Mcm10 regulates DNA replication elongation by stimulating the CMG replicative helicase

Activation of the Mcm2–7 replicative DNA helicase is the committed step in eukaryotic DNA replication initiation. Although Mcm2–7 activation requires binding of the helicase-activating proteins Cdc45 and GINS (forming the CMG complex), an additional protein, Mcm10, drives initial origin DNA unwindin...

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Detalles Bibliográficos
Autores principales:	Lõoke, Marko, Maloney, Michael F., Bell, Stephen P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358725/ https://www.ncbi.nlm.nih.gov/pubmed/28270517 http://dx.doi.org/10.1101/gad.291336.116

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