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No back seat for a progression event—K-RAS as a therapeutic target in CRC
KRAS is the most frequently mutated oncogene in human cancer and plays a central, although poorly understood, role in colorectal cancer (CRC) progression. In this issue of Genes & Development, Boutin and colleagues (pp. 370–382) present a new mouse model of CRC in which the expression of oncogen...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory Press
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358753/ https://www.ncbi.nlm.nih.gov/pubmed/28314765 http://dx.doi.org/10.1101/gad.297630.117 |