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Effects of sevoflurane and clonidine on acid base status and long-term emotional and cognitive outcomes in spontaneously breathing rat pups

BACKGROUND: Numerous experiments in rodents suggest a causative link between exposure to general anaesthetics during brain growth spurt and poor long-lasting neurological outcomes. Many of these studies have been questioned with regard of their translational value, mainly because of extremely long a...

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Detalles Bibliográficos
Autores principales: Almenrader, Nicole, Colucci, Paola, De Castro, Valentina, Valeri, Daniela, Palmery, Maura, Trezza, Viviana, Campolongo, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358762/
https://www.ncbi.nlm.nih.gov/pubmed/28319126
http://dx.doi.org/10.1371/journal.pone.0173969