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Juvenile Granulosa Cell Tumor of the Testicle – Report of a Neonatal Case with Positive Alpha-fetoprotein Immunohistochemical Staining
We report on a case of juvenile granulosa cell tumor of the testicle in a neonate, a rare testicular tumor in children. No genital ambiguity, anatomic abnormalities, nor sex chromosome aneuploidy was noted in this patient. In our case, despite positive staining for alpha-fetoprotein which is most co...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358817/ https://www.ncbi.nlm.nih.gov/pubmed/28331810 http://dx.doi.org/10.1016/j.eucr.2017.02.013 |
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author | Dundas, Melissa Horowitz, Mark Sidlow, Richard |
author_facet | Dundas, Melissa Horowitz, Mark Sidlow, Richard |
author_sort | Dundas, Melissa |
collection | PubMed |
description | We report on a case of juvenile granulosa cell tumor of the testicle in a neonate, a rare testicular tumor in children. No genital ambiguity, anatomic abnormalities, nor sex chromosome aneuploidy was noted in this patient. In our case, despite positive staining for alpha-fetoprotein which is most consistent with yolk sac tumors, all clinical, gross anatomic, histologic, and other immunohistologic characteristics of the tumor remained consistent with the diagnosis of juvenile granulosa cell tumor. The alpha-fetoprotein positivity of the tumor remains unexplained. |
format | Online Article Text |
id | pubmed-5358817 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-53588172017-03-22 Juvenile Granulosa Cell Tumor of the Testicle – Report of a Neonatal Case with Positive Alpha-fetoprotein Immunohistochemical Staining Dundas, Melissa Horowitz, Mark Sidlow, Richard Urol Case Rep Pediatrics We report on a case of juvenile granulosa cell tumor of the testicle in a neonate, a rare testicular tumor in children. No genital ambiguity, anatomic abnormalities, nor sex chromosome aneuploidy was noted in this patient. In our case, despite positive staining for alpha-fetoprotein which is most consistent with yolk sac tumors, all clinical, gross anatomic, histologic, and other immunohistologic characteristics of the tumor remained consistent with the diagnosis of juvenile granulosa cell tumor. The alpha-fetoprotein positivity of the tumor remains unexplained. Elsevier 2017-03-16 /pmc/articles/PMC5358817/ /pubmed/28331810 http://dx.doi.org/10.1016/j.eucr.2017.02.013 Text en © 2017 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Pediatrics Dundas, Melissa Horowitz, Mark Sidlow, Richard Juvenile Granulosa Cell Tumor of the Testicle – Report of a Neonatal Case with Positive Alpha-fetoprotein Immunohistochemical Staining |
title | Juvenile Granulosa Cell Tumor of the Testicle – Report of a Neonatal Case with Positive Alpha-fetoprotein Immunohistochemical Staining |
title_full | Juvenile Granulosa Cell Tumor of the Testicle – Report of a Neonatal Case with Positive Alpha-fetoprotein Immunohistochemical Staining |
title_fullStr | Juvenile Granulosa Cell Tumor of the Testicle – Report of a Neonatal Case with Positive Alpha-fetoprotein Immunohistochemical Staining |
title_full_unstemmed | Juvenile Granulosa Cell Tumor of the Testicle – Report of a Neonatal Case with Positive Alpha-fetoprotein Immunohistochemical Staining |
title_short | Juvenile Granulosa Cell Tumor of the Testicle – Report of a Neonatal Case with Positive Alpha-fetoprotein Immunohistochemical Staining |
title_sort | juvenile granulosa cell tumor of the testicle – report of a neonatal case with positive alpha-fetoprotein immunohistochemical staining |
topic | Pediatrics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358817/ https://www.ncbi.nlm.nih.gov/pubmed/28331810 http://dx.doi.org/10.1016/j.eucr.2017.02.013 |
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