Cargando…

Elevated Expression of Immunoreceptor Tyrosine-Based Inhibitory Motif (TIGIT) on T Lymphocytes is Correlated with Disease Activity in Rheumatoid Arthritis

BACKGROUND: It is well known that lymphocytes play an important role in rheumatoid arthritis (RA). T cell immunoreceptors with immunoglobulin (Ig) and immunoreceptor tyrosine-based inhibitory motif (TIGIT) have immunosuppressive co-stimulatory molecules that mediate inhibitory effects, but their rol...

Descripción completa

Detalles Bibliográficos
Autores principales:	Luo, Qing, Deng, Zhen, Xu, Chuxin, Zeng, Lulu, Ye, Jianqing, Li, Xue, Guo, Yang, Huang, Zikun, Li, Junming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2017
Materias:	Clinical Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358849/ https://www.ncbi.nlm.nih.gov/pubmed/28282368 http://dx.doi.org/10.12659/MSM.902454

Ejemplares similares

Expression of T-cell immunoreceptor with immunoglobulin and tyrosine-based inhibitory motif domains (TIGIT) in anaplastic thyroid carcinoma
por: Nakazawa, Tadao, et al.
Publicado: (2022)

Comprehensive analysis of long non-coding RNA and mRNA expression profiles in rheumatoid arthritis
por: Luo, Qing, et al.
Publicado: (2017)

Elevated expression of TIGIT on CD3(+)CD4(+) T cells correlates with disease activity in systemic lupus erythematosus
por: Luo, Qing, et al.
Publicado: (2017)

Psoriasiform Dermatitis Related with T-Cell Immunoreceptor with Immunoglobulin and Immunoreceptor Tyrosine-Based Inhibitory Motif Domains Inhibitor in a Patient with Non-Small-Cell Lung Cancer
por: Choi, YoungHwan, et al.
Publicado: (2020)

Microglial Immunoreceptor Tyrosine-Based Activation and Inhibition Motif Signaling in Neuroinflammation
por: Linnartz, Bettina, et al.
Publicado: (2010)

CD155 mutation (Ala67Thr) increases the binding affinity for and the signaling via an inhibitory immunoreceptor TIGIT
por: Matsuo, Tomohei, et al.
Publicado: (2022)

Increased TIGIT(+)PD‑1(+)CXCR5(‑)CD4(+)T cells are associated with disease activity in rheumatoid arthritis
por: Luo, Qing, et al.
Publicado: (2022)

Testing the role of the FcγRIIB immunoreceptor tyrosine-based inhibitory motif in regulation of the B cell immune response
por: Vuyyuru, Raja, et al.
Publicado: (2015)

The immunoreceptor tyrosine-based activation motif (ITAM) -related factors are increased in synovial tissue and vasculature of rheumatoid arthritic joints
por: Crotti, Tania N, et al.
Publicado: (2012)

Discovering immunoreceptor coupling and organization motifs
por: Reth, Michael
Publicado: (2023)

Cytoskeletal Polarization of T Cells Is Regulated by an Immunoreceptor Tyrosine-based Activation Motif–dependent Mechanism
por: Lowin-Kropf, Bente, et al.
Publicado: (1998)

Cross Talk between Inhibitory Immunoreceptor Tyrosine-Based Activation Motif-Signaling and Toll-Like Receptor Pathways in Macrophages and Dendritic Cells
por: Hirsch, Ivan, et al.
Publicado: (2017)

Distinct roles of immunoreceptor tyrosine‐based motifs in immunosuppressive indoleamine 2,3‐dioxygenase 1
por: Albini, Elisa, et al.
Publicado: (2016)

Role of Hemin in the Immune Response of T Follicular Helper Lymphocytes Expressing T-Cell Immunoreceptor with Immunoglobulin and Immunoreceptor Tyrosine-Based Inhibitory Domains, Programmed Cell Death-1, and Interleukin-21 in Allo-Auto Positive and Negative Thalassemia
por: Tambunan, Betty Agustina, et al.
Publicado: (2023)

The microglial immunoreceptor tyrosine‐based motif‐Syk signaling pathway is a promising target of immunotherapy for Alzheimer's disease
por: Wang, Shoutang, et al.
Publicado: (2023)

Integrative analysis of long non-coding RNAs and messenger RNA expression profiles in systemic lupus erythematosus
por: Luo, Qing, et al.
Publicado: (2018)

Syk-dependent Phosphorylation of CLEC-2: A NOVEL MECHANISM OF HEM-IMMUNORECEPTOR TYROSINE-BASED ACTIVATION MOTIF SIGNALING
por: Séverin, Sonia, et al.
Publicado: (2011)

Immunoreceptors on neutrophils
por: van Rees, Dieke J., et al.
Publicado: (2016)

C35 overexpression defines subsets of human breast cancer and its immunoreceptor tyrosine-based activation motif represents a novel treatment target
por: Katz, E, et al.
Publicado: (2008)

Fc Receptors as Adaptive Immunoreceptors
por: Daëron, Marc
Publicado: (2014)

Dendritic cell immunoreceptor (DCIR) is associated with anti-cyclic citrullinated peptides (anti-CCP) antibody - negative rheumatoid arthritis in Chinese Han population
por: Guo, Jianping, et al.
Publicado: (2012)

TIGIT is a key inhibitory checkpoint receptor in lymphoma
por: Godfrey, James, et al.
Publicado: (2023)

Interference with Immunoglobulin (Ig)α Immunoreceptor Tyrosine–Based Activation Motif (Itam) Phosphorylation Modulates or Blocks B Cell Development, Depending on the Availability of an Igβ Cytoplasmic Tail
por: Kraus, Manfred, et al.
Publicado: (2001)

Decreased ALKBH5, FTO, and YTHDF2 in Peripheral Blood Are as Risk Factors for Rheumatoid Arthritis
por: Luo, Qing, et al.
Publicado: (2020)

Tyrosine kinases in rheumatoid arthritis
por: Okamoto, Hiroshi, et al.
Publicado: (2011)

The immunoreceptor adapter protein DAP12 suppresses B lymphocyte–driven adaptive immune responses
por: Nakano-Yokomizo, Takako, et al.
Publicado: (2011)

Roles for the FCRL6 Immunoreceptor in Tumor Immunology
por: Davis, Randall S.
Publicado: (2020)

TIGIT: an immune checkpoint beyond T cells in chronic lymphocytic leukemia
por: Seiffert, Martina
Publicado: (2023)

Circular RNAs Hsa_circ_0002715 and Hsa_circ_0035197 in Peripheral Blood Are Novel Potential Biomarkers for New-Onset Rheumatoid Arthritis
por: Luo, Qing, et al.
Publicado: (2019)

Critical Role for an Acidic Amino Acid Region in Platelet Signaling by the HemITAM (Hemi-immunoreceptor Tyrosine-based Activation Motif) Containing Receptor CLEC-2 (C-type Lectin Receptor-2)
por: Hughes, Craig E., et al.
Publicado: (2013)

Tumor-derived extracellular vesicles regulate tumor-infiltrating regulatory T cells via the inhibitory immunoreceptor CD300a
por: Nakazawa, Yuta, et al.
Publicado: (2021)

Increased frequency of TIGIT+ CD4 T Cell subset in autoantibody-positive first-degree relatives of patients with rheumatoid arthritis
por: Anaparti, Vidyanand, et al.
Publicado: (2022)

Serum C-X-C motif chemokine 13 is elevated in early and established rheumatoid arthritis and correlates with rheumatoid factor levels
por: Jones, Jonathan D, et al.
Publicado: (2014)

Tyrosine Kinase Inhibitors for the Treatment of Rheumatoid Arthritis
por: Gomez-Puerta, Jose A., et al.
Publicado: (2013)

Structure and dynamics of Toll immunoreceptor activation in the mosquito Aedes aegypti
por: Saucereau, Yoann, et al.
Publicado: (2022)

Helios but not CD226, TIGIT and Foxp3 is a Potential Marker for CD4(+) Treg Cells in Patients with Rheumatoid Arthritis
por: Yang, Mengru, et al.
Publicado: (2019)

Platelet/Lymphocyte, Lymphocyte/Monocyte, and Neutrophil/Lymphocyte Ratios as Biomarkers in Patients with Rheumatoid Arthritis and Rheumatoid Arthritis-Associated Interstitial Lung Disease
por: Chen, Qiang, et al.
Publicado: (2019)

TIGIT in cancer immunotherapy
por: Chauvin, Joe-Marc, et al.
Publicado: (2020)

PB2392: MRNA IDENTIFICATION OF TIGIT IN PERITUMORAL LYMPHOCYTES IN CLASSICAL HODGKIN DISEASE
por: Annibali, Ombretta, et al.
Publicado: (2023)

The immunomodulatory molecule TIGIT is expressed by chronic lymphocytic leukemia cells and contributes to anergy
por: Arruga, Francesca, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_9hg7iufegqemrvnfuhgctukhle