A reported 20-gene expression signature to predict lymph node-positive disease at radical cystectomy for muscle-invasive bladder cancer is clinically not applicable

BACKGROUND: Neoadjuvant chemotherapy (NAC) for muscle-invasive bladder cancer (MIBC) provides a small but significant survival benefit. Nevertheless, controversies on applying NAC remain because the limited benefit must be weight against chemotherapy-related toxicity and the delay of definitive loca...

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Detalles Bibliográficos
Autores principales: van Kessel, Kim E. M., van de Werken, Harmen J. G., Lurkin, Irene, Ziel – van der Made, Angelique C. J., Zwarthoff, Ellen C., Boormans, Joost L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358850/
https://www.ncbi.nlm.nih.gov/pubmed/28319171
http://dx.doi.org/10.1371/journal.pone.0174039

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