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Preexposure of MCF-7 breast cancer cell line to dexamethasone alters the cytotoxic effect of paclitaxel but not 5-fluorouracil or epirubicin chemotherapy

PURPOSE: Glucocorticoids (GCs) are often administered prior to any chemotherapeutics to prevent the secondary effects of anticancer agents. Glucocorticoid receptors (GRs) are expressed in several types of cancer cells, particularly in several histological types of breast cancer. Activation of GRs is...

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Detalles Bibliográficos
Autores principales: Buxant, Frederic, Kindt, Nadège, Noël, Jean-Christophe, Laurent, Guy, Saussez, Sven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358959/
https://www.ncbi.nlm.nih.gov/pubmed/28352202
http://dx.doi.org/10.2147/BCTT.S120005