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Changes in the number of CD31(−)CD45(−)Sca-1(+) cells and Shh signaling pathway involvement in the lungs of mice with emphysema and relevant effects of acute adenovirus infection
BACKGROUND: COPD is a leading cause of mortality worldwide, and cigarette smoke is a pivotal risk factor. Adenovirus is a common cause of acute exacerbations of COPD and expedites COPD progression. Lung stem/progenitor cells play an important role in the development of COPD, while the relevant mecha...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Dove Medical Press
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359003/ https://www.ncbi.nlm.nih.gov/pubmed/28352167 http://dx.doi.org/10.2147/COPD.S129871 |