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TCF21 functions as a tumor suppressor in colorectal cancer through inactivation of PI3K/AKT signaling

Colorectal cancer (CRC) has become a major public health problem, ranking as the third most common type of cancer. Our previous study has revealed that TCF21 is frequently silenced by promoter hypermethylation in both CRC cell lines and primary CRC, with TCF21 methylation being significantly correla...

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Detalles Bibliográficos
Autores principales: Dai, Youyi, Duan, Huaxin, Duan, Chaojun, Zhu, Hong, Zhou, Rongrong, Pei, Haiping, Shen, Liangfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359128/
https://www.ncbi.nlm.nih.gov/pubmed/28352192
http://dx.doi.org/10.2147/OTT.S118151

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