Zika virus evades interferon-mediated antiviral response through the co-operation of multiple nonstructural proteins in vitro

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Type I interferon (IFN) serves as the first line of defense against invading pathogens. Inhibition of IFN-triggered signaling cascade by Zika virus (ZIKV) plays a critical role for ZIKV to evade antiviral responses from host cells. Here we demonstrate that ZIKV nonstructural proteins NS1, NS4B and N...

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Detalles Bibliográficos
Autores principales: Wu, Yaoxing, Liu, Qingxiang, Zhou, Jie, Xie, Weihong, Chen, Cheng, Wang, Zefang, Yang, Haitao, Cui, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359216/
https://www.ncbi.nlm.nih.gov/pubmed/28373913
http://dx.doi.org/10.1038/celldisc.2017.6
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