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Curcumin Improves Palmitate-Induced Insulin Resistance in Human Umbilical Vein Endothelial Cells by Maintaining Proteostasis in Endoplasmic Reticulum

Dysfunction of proteasome and autophagy will result in disturbance of endoplasmic reticulum (ER) proteostasis, and thus lead to long-term and chronic ER stress and subsequent unfolded protein response (UPR), which is implicated in the occurrence and development of insulin resistance. Curcumin exerts...

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Detalles Bibliográficos
Autores principales: Ye, Mao, Qiu, Hong, Cao, Yingkang, Zhang, Min, Mi, Yan, Yu, Jing, Wang, Changhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359258/
https://www.ncbi.nlm.nih.gov/pubmed/28377722
http://dx.doi.org/10.3389/fphar.2017.00148