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Two Types of Receptive Field Dynamics in Area V4 at the Time of Eye Movements?

How we perceive the world as stable despite the frequent disruptions of the retinal image caused by eye movements is one of the fundamental questions in sensory neuroscience. Seemingly convergent evidence points towards a mechanism which dynamically updates representations of visual space in anticip...

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Autores principales: Hartmann, Till S., Zirnsak, Marc, Marquis, Michael, Hamker, Fred H., Moore, Tirin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359274/
https://www.ncbi.nlm.nih.gov/pubmed/28377700
http://dx.doi.org/10.3389/fnsys.2017.00013
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author Hartmann, Till S.
Zirnsak, Marc
Marquis, Michael
Hamker, Fred H.
Moore, Tirin
author_facet Hartmann, Till S.
Zirnsak, Marc
Marquis, Michael
Hamker, Fred H.
Moore, Tirin
author_sort Hartmann, Till S.
collection PubMed
description How we perceive the world as stable despite the frequent disruptions of the retinal image caused by eye movements is one of the fundamental questions in sensory neuroscience. Seemingly convergent evidence points towards a mechanism which dynamically updates representations of visual space in anticipation of a movement (Wurtz, 2008). In particular, receptive fields (RFs) of neurons, predominantly within oculomotor and attention related brain structures (Duhamel et al., 1992; Walker et al., 1995; Umeno and Goldberg, 1997), are thought to “remap” to their future, post-movement location prior to an impending eye movement. New studies (Neupane et al., 2016a,b) report observations on RF dynamics at the time of eye movements of neurons in area V4. These dynamics are interpreted as being largely dominated by a remapping of RFs. Critically, these observations appear at odds with a previous study reporting a different type of RF dynamics within the same brain structure (Tolias et al., 2001), consisting of a shrinkage and shift of RFs towards the movement target. Importantly, RFs have been measured with different techniques in those studies. Here, we measured V4 RFs comparable to Neupane et al. (2016a,b) and observe a shrinkage and shift of RFs towards the movement target when analyzing the immediate stimulus response (Zirnsak et al., 2014). When analyzing the late stimulus response (Neupane et al., 2016a,b), we observe RF shifts resembling remapping. We discuss possible causes for these shifts and point out important issues which future studies on RF dynamics need to address.
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spelling pubmed-53592742017-04-04 Two Types of Receptive Field Dynamics in Area V4 at the Time of Eye Movements? Hartmann, Till S. Zirnsak, Marc Marquis, Michael Hamker, Fred H. Moore, Tirin Front Syst Neurosci Neuroscience How we perceive the world as stable despite the frequent disruptions of the retinal image caused by eye movements is one of the fundamental questions in sensory neuroscience. Seemingly convergent evidence points towards a mechanism which dynamically updates representations of visual space in anticipation of a movement (Wurtz, 2008). In particular, receptive fields (RFs) of neurons, predominantly within oculomotor and attention related brain structures (Duhamel et al., 1992; Walker et al., 1995; Umeno and Goldberg, 1997), are thought to “remap” to their future, post-movement location prior to an impending eye movement. New studies (Neupane et al., 2016a,b) report observations on RF dynamics at the time of eye movements of neurons in area V4. These dynamics are interpreted as being largely dominated by a remapping of RFs. Critically, these observations appear at odds with a previous study reporting a different type of RF dynamics within the same brain structure (Tolias et al., 2001), consisting of a shrinkage and shift of RFs towards the movement target. Importantly, RFs have been measured with different techniques in those studies. Here, we measured V4 RFs comparable to Neupane et al. (2016a,b) and observe a shrinkage and shift of RFs towards the movement target when analyzing the immediate stimulus response (Zirnsak et al., 2014). When analyzing the late stimulus response (Neupane et al., 2016a,b), we observe RF shifts resembling remapping. We discuss possible causes for these shifts and point out important issues which future studies on RF dynamics need to address. Frontiers Media S.A. 2017-03-21 /pmc/articles/PMC5359274/ /pubmed/28377700 http://dx.doi.org/10.3389/fnsys.2017.00013 Text en Copyright © 2017 Hartmann, Zirnsak, Marquis, Hamker and Moore. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution and reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Hartmann, Till S.
Zirnsak, Marc
Marquis, Michael
Hamker, Fred H.
Moore, Tirin
Two Types of Receptive Field Dynamics in Area V4 at the Time of Eye Movements?
title Two Types of Receptive Field Dynamics in Area V4 at the Time of Eye Movements?
title_full Two Types of Receptive Field Dynamics in Area V4 at the Time of Eye Movements?
title_fullStr Two Types of Receptive Field Dynamics in Area V4 at the Time of Eye Movements?
title_full_unstemmed Two Types of Receptive Field Dynamics in Area V4 at the Time of Eye Movements?
title_short Two Types of Receptive Field Dynamics in Area V4 at the Time of Eye Movements?
title_sort two types of receptive field dynamics in area v4 at the time of eye movements?
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359274/
https://www.ncbi.nlm.nih.gov/pubmed/28377700
http://dx.doi.org/10.3389/fnsys.2017.00013
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