Stk38 Modulates Rbm24 Protein Stability to Regulate Sarcomere Assembly in Cardiomyocytes

RNA-binding protein Rbm24 is a key regulator of heart development and required for sarcomere assembly and heart contractility. Yet, its underlying mechanism remains unclear. Here, we link serine/threonine kinase 38 (Stk38) signaling to the regulation of Rbm24 by showing that Rbm24 phosphorylation an...

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Detalles Bibliográficos
Autores principales: Liu, Jing, Kong, Xu, Yew Mun, Lee, Meng Kai, Zhang, Li Yan, Guo, Lin, Yu, Lim, Teck Kwang, Lin, Qingsong, Xu, Xiu Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359592/
https://www.ncbi.nlm.nih.gov/pubmed/28322254
http://dx.doi.org/10.1038/srep44870

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359592/
https://www.ncbi.nlm.nih.gov/pubmed/28322254
http://dx.doi.org/10.1038/srep44870

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