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Stk38 Modulates Rbm24 Protein Stability to Regulate Sarcomere Assembly in Cardiomyocytes
RNA-binding protein Rbm24 is a key regulator of heart development and required for sarcomere assembly and heart contractility. Yet, its underlying mechanism remains unclear. Here, we link serine/threonine kinase 38 (Stk38) signaling to the regulation of Rbm24 by showing that Rbm24 phosphorylation an...
Autores principales: | Liu, Jing, Kong, Xu, Yew Mun, Lee, Meng Kai, Zhang, Li Yan, Guo, Lin, Yu, Lim, Teck Kwang, Lin, Qingsong, Xu, Xiu Qin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359592/ https://www.ncbi.nlm.nih.gov/pubmed/28322254 http://dx.doi.org/10.1038/srep44870 |
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