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Functional confirmation of PLAG1 as the candidate causative gene underlying major pleiotropic effects on body weight and milk characteristics

A major pleiotropic quantitative trait locus (QTL) located at ~25 Mbp on bovine chromosome 14 affects a myriad of growth and developmental traits in Bos taurus and indicus breeds. These QTL have been attributed to two functional variants in the bidirectional promoter of PLAG1 and CHCHD7. Although PL...

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Detalles Bibliográficos
Autores principales:	Fink, Tania, Tiplady, Kathryn, Lopdell, Thomas, Johnson, Thomas, Snell, Russell G., Spelman, Richard J., Davis, Stephen R., Littlejohn, Mathew D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359603/ https://www.ncbi.nlm.nih.gov/pubmed/28322319 http://dx.doi.org/10.1038/srep44793

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