Use of sildenafil citrate in a cat with Eisenmenger’s syndrome and an atrial septal defect

A 2-year-old male neutered Siamese cat presenting with weakness and dyspnoea was diagnosed with an atrial septal defect and pulmonary hypertension, which resulted in right-to-left shunting (Eisenmenger’s syndrome). The cat was treated with sildenafil (0.25–0.6 mg/kg) for 10 months. There were no app...

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Detalles Bibliográficos
Autores principales: Chow, Ke Shuan, Beijerink, Niek J, Ettinger, Stephen, Fliegner, Reuben, Beatty, Julia A, Barrs, Vanessa R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359795/
https://www.ncbi.nlm.nih.gov/pubmed/28491344
http://dx.doi.org/10.1177/2055116915579680
Descripción
Sumario:A 2-year-old male neutered Siamese cat presenting with weakness and dyspnoea was diagnosed with an atrial septal defect and pulmonary hypertension, which resulted in right-to-left shunting (Eisenmenger’s syndrome). The cat was treated with sildenafil (0.25–0.6 mg/kg) for 10 months. There were no apparent treatment-related adverse effects. Improvement in clinical signs was noted, although increasing doses of sildenafil were required. After 10 months the cat significantly deteriorated and was euthanased.

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