Use of sildenafil citrate in a cat with Eisenmenger’s syndrome and an atrial septal defect

A 2-year-old male neutered Siamese cat presenting with weakness and dyspnoea was diagnosed with an atrial septal defect and pulmonary hypertension, which resulted in right-to-left shunting (Eisenmenger’s syndrome). The cat was treated with sildenafil (0.25–0.6 mg/kg) for 10 months. There were no app...

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Autores principales: Chow, Ke Shuan, Beijerink, Niek J, Ettinger, Stephen, Fliegner, Reuben, Beatty, Julia A, Barrs, Vanessa R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359795/
https://www.ncbi.nlm.nih.gov/pubmed/28491344
http://dx.doi.org/10.1177/2055116915579680
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author Chow, Ke Shuan
Beijerink, Niek J
Ettinger, Stephen
Fliegner, Reuben
Beatty, Julia A
Barrs, Vanessa R
author_facet Chow, Ke Shuan
Beijerink, Niek J
Ettinger, Stephen
Fliegner, Reuben
Beatty, Julia A
Barrs, Vanessa R
author_sort Chow, Ke Shuan
collection PubMed
description A 2-year-old male neutered Siamese cat presenting with weakness and dyspnoea was diagnosed with an atrial septal defect and pulmonary hypertension, which resulted in right-to-left shunting (Eisenmenger’s syndrome). The cat was treated with sildenafil (0.25–0.6 mg/kg) for 10 months. There were no apparent treatment-related adverse effects. Improvement in clinical signs was noted, although increasing doses of sildenafil were required. After 10 months the cat significantly deteriorated and was euthanased.
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spelling pubmed-53597952017-05-10 Use of sildenafil citrate in a cat with Eisenmenger’s syndrome and an atrial septal defect Chow, Ke Shuan Beijerink, Niek J Ettinger, Stephen Fliegner, Reuben Beatty, Julia A Barrs, Vanessa R JFMS Open Rep Case Report A 2-year-old male neutered Siamese cat presenting with weakness and dyspnoea was diagnosed with an atrial septal defect and pulmonary hypertension, which resulted in right-to-left shunting (Eisenmenger’s syndrome). The cat was treated with sildenafil (0.25–0.6 mg/kg) for 10 months. There were no apparent treatment-related adverse effects. Improvement in clinical signs was noted, although increasing doses of sildenafil were required. After 10 months the cat significantly deteriorated and was euthanased. SAGE Publications 2015-04-28 /pmc/articles/PMC5359795/ /pubmed/28491344 http://dx.doi.org/10.1177/2055116915579680 Text en © The Author(s) 2015 http://creativecommons.org/licenses/by-nc/3.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page(http://www.uk.sagepub.com/aboutus/openaccess.htm).
spellingShingle Case Report
Chow, Ke Shuan
Beijerink, Niek J
Ettinger, Stephen
Fliegner, Reuben
Beatty, Julia A
Barrs, Vanessa R
Use of sildenafil citrate in a cat with Eisenmenger’s syndrome and an atrial septal defect
title Use of sildenafil citrate in a cat with Eisenmenger’s syndrome and an atrial septal defect
title_full Use of sildenafil citrate in a cat with Eisenmenger’s syndrome and an atrial septal defect
title_fullStr Use of sildenafil citrate in a cat with Eisenmenger’s syndrome and an atrial septal defect
title_full_unstemmed Use of sildenafil citrate in a cat with Eisenmenger’s syndrome and an atrial septal defect
title_short Use of sildenafil citrate in a cat with Eisenmenger’s syndrome and an atrial septal defect
title_sort use of sildenafil citrate in a cat with eisenmenger’s syndrome and an atrial septal defect
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359795/
https://www.ncbi.nlm.nih.gov/pubmed/28491344
http://dx.doi.org/10.1177/2055116915579680
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