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Mesenchymal stem cells increase expression of heme oxygenase-1 leading to anti-inflammatory activity in treatment of acute liver failure

BACKGROUND: Mesenchymal stem cells (MSCs) have been studied for the treatment of acute liver failure (ALF) for several years. MSCs may exert their effect via complex paracrine mechanisms. Heme oxygenase (HO) 1, a rate-limiting enzyme in heme metabolism, exerts a wide range of anti-inflammatory, anti...

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Detalles Bibliográficos
Autores principales:	Zhang, Zhi-heng, Zhu, Wei, Ren, Hao-zhen, Zhao, Xin, Wang, Shuai, Ma, Hu-cheng, Shi, Xiao-lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359839/ https://www.ncbi.nlm.nih.gov/pubmed/28320485 http://dx.doi.org/10.1186/s13287-017-0524-3

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